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Once estimated, I show how the liability estimates can then be used to search for likely functional non-synonymous deleterious variants that influence addictive behavior by exploiting the extensive whole genome sequence information that we have for this study.
In order to test whether the variant we identified in CEP120 is disease-causing, we sought to search for likely pathogenic variants in this gene in independent individuals.
The identification of multiple alleles associated with a clinically relevant trait could be extremely important in narrowing the search for likely causal genes.
If the complete architecture (e.g. core sequence, Y/iceberg regions, TM and amphipathic helices) could be combined in a probabilistic fashion with contributions of the individual features weighted by their statistical power, a better more integrative search for likely further remote homologues could be attempted.
Do an Internet search, or contact a travel agent, to search for likely accommodations.
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BBC Earth's Life of Mammals films a group of chimpanzees in Uganda embarking on a frantic hunt, where males set off into the forest searching for likely victims.
After applying these measures to generate a synthetic network, we searched for likely connections between Apc and Cdkn1a using both gene coexpression data and Gene Ontology association rules.
Transcripts were searched for likely protein-coding regions and a non-redundant set of 117,563 putative protein sequences was produced.
Specifically, TIC Genetics searches for likely deleterious mutations that are shared by affected individuals within multiply affected families.
For example, if one study showed results that were completely out of range of the others, we searched for likely reasons explaining the difference and performed a sensitivity analysis excluding that study, when deemed appropriate.
One of the potential applications of synteny is map alignment-based identification of candidate genes for important traits in the crop species by searching for likely candidates in the equivalent region of the model genome.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com