Sentence examples for seamless phase from inspiring English sources

Statistical Aspects of the TNK-S2B Trial of Tenecteplase versus Alteplase in Acute Ischemic Stroke: An Efficient, Dose-Adaptive, Seamless Phase II/III Design.

The recent experimental realization of 2D boron1,2,3,4,5,6,7,8 (i.e., borophene) has spurred broad interest in its unique material attributes such as in-plane anisotropy9, massless Dirac fermions10, and seamless phase intermixing7.

Adaptive seamless phase II/III clinical trial designs allowing treatment selection at an interim analysis have gained much attention because of their potential benefits compared to more conventional drug development programmes with separate trials for individual phases.

We propose a two-stage strategy, called the Limb-Leaf method, to explore the dose-response curve using dose promotion and addition in the context of adaptive seamless Phase II/III trials.

The coexistence of this structure with v1/6−30° phase borophene with parallel HH rows and a seamless phase boundary is shown in the CO-STM image in Fig. 3e, confirming a rotation angle of 30° and thus the identity of this phase as v1/5−30°.

Although there is still a small role for single-arm and non-comparative phase 2 designs, emphasis is placed on the potential role that comparative randomised phase 2 designs such as screening designs, selection designs, discontinuation designs, and adaptive designs, including seamless phase 2/3 designs can have.

24 26 Results from the dose ranging study, Part A of the MOnoclonal anti Body to IL-6Rα In RA patients: A pivotal Trial with X-ra Y (MOBILITY) seamless-design Phase II/III study (NCT01061736), are reported here.

Thus, this study employed a seamless design, incorporating 'Phase II' into a 'Phase III' outcomes trial, as considered further in the Discussion.

"The erratic and shambolic scenes in British politics over the past 18 months don't bode well for a seamless accession through phase two," Shona Murray writes.

A three-phase seamless transition method is introduced into the controller.

We describe the design of a seamless, multi-site randomized Phase II/III trial to evaluate an asthma management intervention in urban adolescents with asthma.