Sentence examples for screens hit from inspiring English sources

DSF has been successfully employed in prior screens, hit characterization and validation, selectivity profiling of kinase inhibitors, and the characterization of ligand interactions with GRKs.

Yao is playing as if his life depended on it, blocking shots, setting screens, hitting his shots.

Based on a high throughput screening hit, pyrrolopyrimidine inhibitors of the Akt kinase are explored.

An orally active GPR4 antagonist 39c was developed, starting from a high throughput screening hit 1.

Herein, we establish structure activity relationships of 51 N-phenylphthalimide analogs of the screening hit 1.

Application of structure-based design to screening hit 1 yielded sub-micromolar inhibitors.

Beginning with a diaminotriazine screening hit, several series of novel, tricyclic gamma-secretase modulators (GSMs) were designed.

A series of amino-pyrimidines was developed based upon an initial kinase cross-screening hit from a CDK2 program.

A screening hit 1 against Trypanosoma brucei methionyl-tRNA synthetase was optimized using a structure-guided approach.

A novel class of Hsp90 inhibitors, structurally distinct from previously reported scaffolds, was developed from rational design and optimization of a compound library screen hit.

A series of 2-oxopiperazine derivatives were designed from the pyrrolopiperazinone cell-based screening hit 4 as a dengue virus inhibitor.