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Evolutionary approaches are often undirected and mutagen-based yielding numerous mutations, which need elaborate screenings to identify relevant targets.
Since joining the lab in November 2017, she is setting up high-throughput genetic screenings to identify causal genes of insulin resistance and related cardiovascular metabolic diseases.
The sequence comparison tools developed in this work can also be used in other types of screenings to identify genes involved in other biological processes unique to each sibling Drosophila species.
The community screenings to identify undiagnosed cases were conducted in churches, workplaces, and other organizations.
It is conceivable that hiMAC will be applied for genome-wide screenings to identify factors involved in cell cycle phase-dependent processes.
Collectively, these results demonstrate that hESC-atrial CMs are a valuable model for preclinical drug screenings to identify effective atrial-selective compounds.
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Indeed, several genome-wide screenings succeed to identify host proteins that participate in every step of influenza virus infection [3], [4], [5], [6].
This proposal calls for the initiation of national population-screening programs to identify carriers of cancer gene mutations for long-term, large-scale analysis of longitudinal clinical data to aid in prevention and early detection of disease.
Our study used a fragment-screening approach to identify a series of compounds that inhibit the Tob-CNOT7 interaction.
Thus, HRMA can be used only as a pre-screening technique to identify the presence or absence of a mutation.
61 Therefore, the analysis of somatic KRAS has been recommended as a pre-screening test to identify CRC patients eligible for MUTYH germline molecular genetic testing.
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screenings to eliminate
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