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Urine screening was used as an objective assessment of treatment adherence.
X-ray crystallographic fragment screening was used to identify fragment hits and their binding modes.
The high-throughput screening was used to determine binodal curve and tie-lines as well as protein distribution and recovery.
High-throughput screening was used to rapidly optimize formulations with desirable nano-architectures and low in vitro cytotoxicity.
Methods: A two-group quasi-experimental design with baseline and post-intervention assessment and a 12-month follow-up on screening was used in the study.
Here, NMR screening was used to discover non-peptide leads against this target and resulted in the discovery of a new benzamide 1 series.
This screening was used to separate the 111In-octreotide patients into two groups: one with no confirmed liver tumours (111In-octreotide/radtech and one with confirmed liver tumours (111In-octreotide/radtech. Fig. 1 Patient flow of the 111In-octreotide investigations.
The structure-based library design approach, including the focused library design (Virtual Combinatorial Library Design) and virtual screening was used to select the 1,4-dihydropyrimidine scaffold for simultaneous inhibition of both enzyme pathways (COX-1/COX-2 and 5-LOX).
Charge-state screening was used to reject singly charged ions.
Blue-white screening was used to identify mutants, as described [36].
Structure-based virtual screening was used to enrich sets of biologically active amino acids at two positions in the glycopeptides.
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