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In conclusion, this multicellular co-culture system could become a useful tool for toxicity screening to evaluate the specific effects of neurotoxic, neuroinflammatory and neuroinfectious agents on each cell type separately and would provide improved conditions to develop a BBB dynamic model using human primary cells in the future.
The altered expression of KGF/KGFR observed in some cancers suggests that a screening to evaluate the expression of KGFR and KGF in tumor biopsies might turn out useful as prognostic marker.
>: MIC value is above the range tested In this study, we performed an initial screening to evaluate the potential of the oCelloScope system to perform rapid AST.
Population-based prospective cohort study with baseline screening, to evaluate the performance of the FINDRISC, DANISH, DESIR, ARIC and QDScore, against the gold standard tests: Fasting plasma glucose, oral glucose tolerance and/or HbA1c.
To this end, we performed high-throughput chemical compound screening to evaluate the validity of our results under more physiological conditions and found several compounds that reduce cell viability by inhibiting our predicted targets.
In a study conducted in the United States, Ramsey and colleagues used a validated microsimulation model [ 32] adopting a societal perspective (i.e. analysis including direct and indirect costs of screening) to evaluate the clinical and economic implications of implementing a CRC screening programme based on family history in the United States.
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The particle and exposure characterization in all toxicological articles was screened, to evaluate the quality of the presented data and the validity of the hazard assessment in the review presented in Table 2.
A wide range of cancer cell lines have been screened to evaluate the anticancer potential and selectivity of ON01910.Na.
A number of human and mouse cancer cell lines have been screened to evaluate the potential of TAL and exhibited an inhibitory effect at an IC50 of 0.2 1.3 μM.
SBE13 showed a 1000-fold greater inhibition selectivity among PLK family members, and a wide range of cancer cell lines have been screened to evaluate the anti-proliferative effect of SBE13, and it caused G2/M arrest at higher concentrations (http://www.tandfonline.com/doi/pdf/10.4161/cc.9.3.10721).com/doi/pdf/10.4161/cc.9.3.10721
As UPI test is a simple screening test to evaluate the mental state of university students, slightly higher UPI scores in healthy subjects do not always reflect a preclinical stage of mental disease.
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