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The measurement of these tests is not only useful for screening the status of AS disease, but also useful for the determination of progression and therapeutic effects of AS [ 14] as well as other pathologic conditions associated with low back pain [ 7, 10, 13, 15].
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Therefore, we developed a COBRA based method of screening the methylation status at the evolutionary conserved CpG position −77 in the FOXP3 promoter region.
Screening the smoking status of all patients, initiation of appropriate smoking cessation intervention and adequate postdischarge follow-up should be integrated into routine clinical practice at hospitals implementing a 'smoke-free' policy.
In addition, when these models are trained, they can be used for screening the biological activity status of a set of chemicals faster than ligand protein docking approaches [17].
Moreover, its use has been reported in some studies screening the mental health status of some of the immigrant groups and displaced persons in Europe [ 28- 31].
The assay was subsequently used to screen the genomic status of these two genes in ten primary ESCC tumors.
To screen the methylation status of selected DMRs in a larger sample set we used methylation-specific PCR (MSP) [ 33].
The Ministry of Health, Labour and Welfare, Japan, recommend midwives and public health nurses to screen the depressive status with the EPDS at 1-month postpartum, and to initiate appropriate procedures for positive cases.
It also protects against polio, diphtheria, whooping cough and tetanus, screens the nutritional status of each child, and offers vitamin A supplementation, oral rehydration salts and water purification tablets.
Our group has already screened the KIF5B/RET gene status using RT-PCR assay (Yokota et al., unpubl. ms).
Taking advantages of genome-scale coverage and single-base resolution of our dRRBS technology, we extensively screened the DNA methylation status of these two cell lines.
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