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Our combined approach started with screening the human genome for protease genes.
After selectively screening the human genome with RepeatMasker, we detected 1,004,931 dimeric Alu elements, 2,268 of which were considered to be unambiguous nested insertions.
Screening the human genome for snoRNA-like sequences revealed that most of them proved to be nonfunctional retrogenes with substitutions in the conserved regions [ 16, 30].
Motivation: High-throughput-sequencing (HTS) technologies are the method of choice for screening the human genome for rare sequence variants causing susceptibility to complex diseases.
Screening the human death-associated protein 3 (hDAP3) gene promoter with the 125 TFBS motifs, these nine transcriptional factors presented the highest-scoring sites (Table 2).
Recently, Vogelstein and coworkers have developed a new technique whereby mutations in APC, MSH2, or MLH1 may be detected by converting diploid cells to haploid cells by selectively fusing with mouse cells and screening the human chromosome of interest.
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In this study, we screened the human proteome for domain annotation using the PROSITE web tool [20].
In this context, we chose to screen the human lung proteins against Esat6, given that the primary site of infection is the human lung [7].
To test the hypothesis that a 3' splice site-like sequence juxtaposed to U/C rich sequence may represent a general motif associated with alternative splicing, we screened the human genome for genes containing such sequences.
We screened the human collection from the National Antimicrobial Resistance Monitoring System 2000 for ESC resistance mechanisms.
We set out to screen the human genome for LTSM-positive genes to generate hypotheses about the motif's function.
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