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In the realm of cancer research, the work by Kessler et al (2012) highlights one of the great strengths of genome-scale RNAi screening: the ability to identify tumour vulnerabilities that are not oncogenic per se.
Although the 'low resolution' histone- and chromatin-binding assays (i.e., AlphaLisa and in situ cell extraction) developed here are well suited for compound screening, the ability to map the genome-wide locations of proteins and drug targets at 'high resolution' is critical for our understanding of normal and disease biology.
It is of importance that, in addition to facilitating analyses of drug-resistance mechanisms and its applicability in compound screening, the ability to expand CSC-enriched populations in vitro provides a sufficient number of cells for analyses by emerging technologies such as mass spectrometry-based proteomics.
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This study was to screen the ability of biofilm formation by Campylobacter jejuni strains found in New Zealand, and investigate the biofilm growth of C. jejuni in a controlled mixed-microbial population that includes five different bacteria.
The HLA-stability ELISA allowed us to rapidly screen the ability of each peptide to rescue various HLA complexes from denaturation 22.
To assess their role during sexual stage development, we initially screened the ability of the mutants to form viable ookinetes in vitro.
We used this measure to screen the ability of the children to participate in further ToM assessment and to gain additional information on ToM.
To further investigate the substrate specificities of PaLPMO9s, we used the method based on H2O2 detection to rapidly screen the ability of PaLPMO9s to interact with a range of potential hemicellulosic substrates.
This rat model is widely used to screen the ability of new anti-inflammatory agents to reduce local edema induced in the rat paw by injection of an irritant agent [ 44].
Additionally, rapidly sequencing and screening the aseismic ability of a large number school buildings to make maintenance and management decisions is extremely difficult.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com