Exact(3)
Almost all of the numerous examples reported in the literature utilize high-throughput screening systems based on suitable analytical techniques.
In order to allow processing of the displayed antibody in a eukaryotic environment, screening systems based on viruses and mammalian cells have been described.
Alternatively, investigators have chosen to design their experimental screening systems based on understanding the consequences of particular tumour suppressor gene deficiency.
Similar(57)
Results of an automatic DR screening system based on AM-FM exhibit strong promise in addressing this problem.
Due to the poor sensitivities and specificities of antibody based point of need devices, we have developed a low-cost and reliable latent tuberculosis infection (LTBI) screening system based on enzyme linked aptamers which are cost effective and chemically stable.
The source will be capable of delivering a flux >1 × 107 n/(cm2 s) at a distance of 2.5 m from the target and will allow full testing and demonstration of a cargo screening system based on neutron stimulated SNM signatures.
To overcome these obstacles, a screening system based on random peptide libraries displayed directly on AAV capsids has recently been developed were the AAV library particles are amplified based on binding, uptake and viral gene expression in the target cell via adenoviral helper co-infection [14], [33].
A PCR screening system based on primer sets derived from genetically mapped ESTs on chromosome 3H was used for clone selection in a BAC library developed from cultivar "Haruna Nijo".
In addition to the classes listed above, Yermolina et al. reported a newly developed antifiloviral screening system based on EBOV-GP pseudotyped HIV particles to identify compound 8a, which selectively inhibited EBOV and MARV infection in human cells.
Here, we describe the construction of an L-arabinose transporter screening system based on a S. cerevisiae strain without a hexose/pentose transporter expressing an L-arabinose utilization pathway.
Interestingly, in a loss-of-function screening system based on intracellular expression of single-domain antibodies, Inoue et al (2007) found that hnRNP K is a potential target for metastasis and its cytoplasmic accumulation may mediate its role in cell migration and metastasis.
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