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By using the real participation- and Chlamydia positivity rates from the first screening round (Table 1), we determined the minimal decline needed to find a significant effect of screening on Chlamydia positivity.
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In Funen, on average 52,938 women were invited to mammography screening during each of the first four screening rounds (Table 1).
The proportions of screen-positive men were greater for NSAID users vs nonusers in all screening rounds (Supplementary Table 2).
The risk of an FP result varied from 3.3 to 12.1% per round, depending on the screening round and age (Table 1).
Outcome after CTC stratified by sex and screening round is shown in table 4. CTC abnormality was commoner in men than in women (632 of 1505 men, 42.0% vs 395 of 1226 women, 32.2%, χ=27.0, p<0.001).
The number of patients undergoing benign biopsy was highest in the first screening round and decreased in subsequent rounds (Table 3).
On average 41,091 women were invited to mammography screening during each of the first five screening rounds in Copenhagen (Table 1).
Some drug companies, which would benefit from wider screening, are associate members of the round table.
Few significant differences in diagnostic outcomes were observed between screening history subgroups in the third round (table 6).
The proportion of women who re-attended after a false-positive referral in their first screening round remained stable over the years (Table 2).
29 Test characteristics of the one-sample and two-sample FIT tests were fitted to the positivity rates and detection rates of advanced neoplasia observed in the first screening round of two Dutch randomised trials (table 1).
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