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The screening of the sequence variations in the 3rd, 4th, 5th and 7th exon of the RAD50 gene pointed out that p.I94L, IVS3-1G>A, c.687delT, p.R224H and p.Q350X were not observed in our leukemia patients or controls.
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In HyPhy all methods can take recombination into account, provided that prior to the selection analysis a screening of the sequences for recombination breakpoints is performed.
The results were manually curated by reverse screening of the sequences with significant similarity hits against the NCBI database using BLAST tools.
A bioinformatics screening of the sequences of 824 human GPCRs uncovered conservation of FBMs in the cytoplasmic regions of 116 nonolfactory GPCRs (Table S1) and 73 olfactory GPCRs (Table S2).
In platypus and opossum, however, screening of the gDNA sequence provided two putative sequences depending on whether the intraexonic splicing occurs in exon 8 or not.
The screening of the TCTCCTCCAC sequence led to the identification of three different classes of TFs (bHLH, bZIP and NAC).
This suggests that CHEK2 analysis in populations where the common founder mutations are rare requires screening of the entire sequence.
Using a comprehensive approach for siRNA screening of the conserved sequences of the N gene, including sequence analysis and functional in vitro tests, we have identified a region for the design of siRNA effective for the control of PPRV, RPV, and MV replication.
However, in a mixed ethnic population, such as is found in most of the United States and Canada, testing involves the complete screening of the coding sequences of the two genes.
We performed a systematic mutation screening of the coding sequences of six of these genes on a cohort of 100 familial and isolated patients diagnosed with HSAN.
A screening of the genome sequences of C. ulcerans 809 and C. ulcerans BR-AD22 with the CRISPRFinder program [ 36] revealed the presence of three loci of so-called clustered regularly interspaced short palindromic repeats (CRISPRs) (Table 3).
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