Sentence examples for screening of the functional from inspiring English sources

Our findings indicate that the organotypic hemisphere cultures used here, having relatively preserved cortico-striatal connections but severed DA input to the striatum, represent a suitable model for preliminary screening of the functional properties of stem cell-derived DA neurons and their integration into host neural circuitries.

A systematical screening of the functional single-nucleotide polymorphisms in the promoter region, 5′-UTR (untranslated region) and 3′-UTR, exons of the ANXA11 gene, and the homogeneity of study participants representing the Chinese Han are the main strengths of this study.

Furthermore, our study illustrates that unbiased quantitative proteomics is an effective method by which to extend the results of genetic screens to the functional biochemical level.

We developed and utilized a cytogenetically normal clonal line of hTERT immortalized human mammary epithelial cells in a fibroblast-enhanced co-culture assay to conduct a genome-wide small interfering RNA (siRNA) screen for evaluation of the functional effect of silencing each gene.

Clique analysis formulates common functional modules and enables easy screening of the co-expression or functional units of gene sets which maps to related target complexes or common pathways of biological function [ 28, 31].

This result is coherent with the strong selection imposed by the functional screen and is similar to previous results concerning the functional screening of the human gut microbiome [ 13].

The screening of CD8 functional performance was made on 48 genes and analyzed using one-way ANOVA and post hoc Tukey's tests, using Prism (GraphPad Software).

Besides choosing a cellular system that is biologically relevant for the screening of candidate functional variants at GWAS loci, as outlined above, attention has to be paid to choosing a suitable genome annotation mark.

Our studies validate the utility of the Swip screen, demonstrate the functional relevance of DA transporter structural elements, and reveal novel genomic loci that encode regulators of DA signaling.

Our results indicated that CDB-fused fluorescent protein can be used to examine the slight gene regulations in the reporter gene system and have the potential to be the system for screening of functional compounds in the future.

The design of the molecularly imprinted polymer (MIP) was based on the results of the computational screening of the library of polymerisable functional monomers.