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Developing new, validated methods for screening of the effects of nanomaterials is a huge and expensive task.
A Design of Experiment (DoE) was employed for the screening of the effects of the formulation variables related to the presence of unloaded microparticle (MPs) on the cement most important mechanical properties.
To do this, we developed a high-throughput assay of myocyte size that would allow for rapid screening of the effects of knocking down TrpC3 and other candidate hypertrophy genes identified in our screens.
In particular, recent advances in the experimental technologies which allow for the large-scale screening of the effects of combinatorial gene deletions are providing an exciting glimpse into the organization of complex genetic networks in terms of revealing novel interacting cellular components and compensatory pathways involved in many cell functions.
Moreover, this first microarray screening of the effects of Gelsemium s. on neurocytes revealed a significant down-regulation of genes for inflammatory response, olfactory transduction and neuron differentiation.
Importantly, the HTP culture method will be useful, in combination with microscopy techniques, for rapid screening of the effects of environmental factors and drugs on breast epithelium homeostasis (e.g., modulators of apical polarity [ 31]).
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Additional file 1: Screening of the effect of xylose on the xylanase activity of the 225 XynA+clones.
Methods following NGS, like GWSS and GWAS, allow for distinguishing neutral from non-neutral markers and thus for screening of the effect of habitat fragmentation on patterns of non-neutral (as compared to neutral) marker variation.
There are significant challenges with screening for the effects of a large number of compounds on human spermatozoa.
Thicker, two-layer reduced graphene oxide sheets show effective screening of the electrostatic effects caused by charge impurities trapped in the substrate.
The most severe mutant in our proteomic screen of the effect of mutations at conserved sites in cdc8 on cellular morphology and function was cdc8 R121A.D131A.E138A (Cranz-Mileva et al., 2013).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com