Homologs of RecA and RpoB were defined by HMM profile screening of Pfam profiles (PF00154, PF08423, PF00562) [74], [74] and TIGRfam profiles (TIGR02012, TIGR02013, TIGR02236, TIGR02237, TIGR02239, TIGR03670) [75], as well as by BLASTP searches [76] using a diverse collection of known family members as query sequences.
Therefore, screening of miRNA profiles in BCSCs and MaSCs seems significant to elucidate the role and mechanism of miRNAs in tumorigenesis of breast cancer.
ELISA and Biacore (Otelfingen, Switzerland) screening of dissociation profiles of selected clones on a high-density coated chip yielded the antibody A3.
We describe here the first report of a high-throughput screening of expression profiles of miRNAs regulated by Nanog in postnatal NSCs and identify a number of miRNAs that are modulated following increased or decreased expression of this transcription factor, suggesting that they might be downstream effectors of Nanog.
This study analyzes metabolomic data from a rice tillering (branching) developmental profile to define a set of biomarker metabolites that reliably captures the metabolite variance of this plant developmental event, and which has potential as a basis for rapid comparative screening of metabolite profiles in relation to change in development, environment, or genotype.
Contrary to the analysis of mRNA profiles, the screening of protein expression profiles allows direct conclusions about the molecular mechanisms involved in a certain condition, because many cellular processes are directly related to the protein functions.
To facilitate screening and extraction of profiles from the database, a Look-Up tool was developed (Additional file 11).
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The effectiveness of a procedure of SPE/TLC screening profiling of impurities was studied on the basis of selected impurities.
