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The study also showed high rates of incident TB over the four years following enrolment, suggesting that serial screening of contacts is a high yield strategy.
The control of tuberculosis is dependent on early identification of cases and timely notification to public health departments to ensure appropriate treatment of cases and screening of contacts.
The Swiss paper analysed the cost of introducing the IGRA in routine screening of contacts and was published in 2006 by Wrighton-Smith and Zellweger [ 15].
Health care facilities could choose to reserve more aggressive interventions, such as screening of contacts and patient cohorting, for patients with isolates that meet this new definition, which appears to more completely detect carbapenemase-producing CRE.
Indications for HIV testing include clinical suspicion, screening of contacts of HIV-infected patients, and routine screening of blood and organ donors, prisoners, intravenous drug users, patients with other sexually transmitted infections, and expatriates pre-employment.
To optimize the yield of contact investigation, the 2 interventions most frequently used in these outbreaks were prioritizing screening of contacts on the basis of TB risk (3, 5, 6, 8 – 18, 18 ) and offering location-based TB screening at specific venues associated with each outbreak, including bars, shelters, and drug houses (5, 6, 10, 13, 14 ).
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Initial and weekly screening of contact Pts was systematically performed.
For screening of contact persons they compared three strategies: 1) no screening, 2) TST only and 3) QFT.
Screening of contact persons is only necessary if no pre-emptive isolation of MRSA patient is conducted.
Two additional weekly screening of contact patients performed using the same culture method identified no additional cases.
Subsequent screening of contact patients in the ICU showed MRSA colonization in three other patients who had ventilatory support at the same time.
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