Sentence examples for screening of alterations from inspiring English sources

Here, we report the first comprehensive screening of alterations in DUB expression in nine human cancers.

For example, a multiplex RT-PCR (mRT-PCR) assay was developed for rapid screening of alterations in prostate cancer genes at miRNA levels.

As we only used 2 3 piglets in each group for initial genome-wide screening of methylation alterations, further validation of DNA methylation alteration of identified key genes were performed on larger sample sets.

Results: A rapid, effective test enabling the screening of DNA alterations in the entire LDL receptor gene was developed.

In this regard, mass spectrometry based mutation profiling is a robust technique that can be applied on frozen or formalin-fixed embedded tissue, and is particularly well-suited for multiplexed screening of hotspot alterations in large patient cohorts [ 40].

Despite being one of the first techniques used for screening of chromosomal alterations in CLL, CGC studies are limited by the requirement of dividing cells in culture and FISH analyses only offer a vision of the genome limited to the specific probes used.

By screening for alterations of a dominant wing vein phenotype we have found modifiers of the DGC that are involved in cytoskeletal organization.

Together these results indicate that zebrafish is a species ideally suited for investigation of ion channels related mutation screening of cardiac alteration important in human.

Although a significant number of cancer-related genes have been identified in the past few decades [ 1], the emergence of technologies that allow genome-wide screening for alterations in large collections of tumors has affected the field of cancer biology in a dramatic way.

In the F1 generation, we sought putative Top2 alleles by screening for alteration of a phenotype that depends on somatic homolog pairing, while in the F2 generation, putative Top2 alleles were identified by their failure to complement a chromosome carrying a deletion of Top2.

Screening for alterations in the Mdm genes in luminal BrCa revealed rare amplification of the Mdm2 gene and no selection for Mdm2 SNP309 in primary tumors.