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To explore alternative screening modalities for detecting ALK fusions, we designed a combination of two transcript-based assays to detect for presence or absence of ALK fusions using NanoString's nCounter technology.
Little similarity exists between the specific screening modalities for the different cancer sites, and a meaningful discussion requires that we examine the approaches for each type of cancer separately.
CT and ultrasound are used as screening modalities for the spleen with MRI helpful for characterisation of lesions.
The lack of proven screening modalities for laryngeal cancer necessitates the search for diagnostic biomarkers for the early detection of this malignancy.
The PLCO study is a multi-centre, randomised trial designed to evaluate screening modalities for prostate, lung, colon, and ovarian cancers (Prorok et al, 2000).
By contrast, for breast, cervix and colorectal cancers, there are well-established screening modalities for the general population, giving potential for screening programmes for cancer patients if they are at increased risk.
Similar(54)
57 Oximetry alone is not a sufficient screening modality for the assessment of sleep disordered breathing.
Other limitations of traditional surveillance approaches include the failure to capture new and emerging screening modalities (eg, virtual colonoscopy for colorectal cancer, MRI for breast cancer detection, or low-dose spiral CT for lung cancer screening among persons at high risk for lung cancer) especially when use is still low.
The most strongly endorsed Advantage items were: "better understand risk of future disease" (mean score of 3.9 on the 1-4 scale); "better rationale for screening modalities" (3.8); "basis to provide preventive guidance to patients" (3.7); and "better address patient's concerns" (3.5).
*Adjusted for age, sex, screening modality, screening centre, allotted time for screening in weeks 1, 2, 6, or 7 after birthday and month for allotted screening appointment.
In addition, the determination of age of the start of screening and inter-screening interval and the threshold of screening modality with alternative image technique for high-risk group may vary with different populations.
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