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Screening intervals were a different story.
Clinical trials did not answer that question because they did not directly compare screening intervals.
The results, the authors say, suggests that for HPV-negative women, the increase in screening intervals for over-40s is justified.
Trentham-Dietz, A. et al. Tailoring breast cancer screening intervals by breast density and risk for women aged 50 years or older: collaborative modeling of screening outcomes.
It based its recommendations on an extensive review of the literature and a computer simulation that incorporated the best available data on mortality, screening techniques, screening intervals, and stop and start ages.
It allows for arbitrary age groups, detection thresholds and screening intervals and may contribute to the design of future screening trials.
However, at more frequent screening intervals, strategies combining vaccination and screening were preferred.
We used discrete event history analysis to model nonadherence to mammography maintenance over three successive annual screening intervals (+ 2 months).Most (54%) women did not maintain screening adherence over 3 years.
Combining this finding with the possibility of lower adherence over longer screening intervals, 5 year screening intervals may be even more attractive.
Even non-cancerous growths can change the recommended screening intervals.
No information on screening intervals was available for this group.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com