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Screening implications have not been modelled.
The data suggesting a possible earlier onset of breast cancer in individuals with NF1 are particularly important, given the possible screening implications.
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Because of its import and its critical contribution to the controversy surrounding LC screening, the implications of overdiagnosis deserve elaboration.
Results from our screening have implications for the design of products for skin lightening and treatment of hyperpigmentation.
Additionally, rates of higher-stage cancers were further increased, suggesting that targeting these groups would allow prevention of more lethal BCs (Brentnall et al.; 2015; Development of a mammographic density adjusted Tyrer-Cuzick model in 50,000 women in a general population breast screening population: implications for risk stratified screening; unpublished).
The examples of empowerment on the page and screen have implications for real-world choices that should be available for women across the globe.
In addition, reporting positive screens has implications for confidentiality and informed consent.
Furthermore, "chemical suppression" screens have implications in the identification of novel functions and therapeutic potentials of existing chemical compounds.
Given the higher risk of diabetes, lack of systematic screening has greater implications for obese adults.
The association of density both with higher cancer incidence (particularly of grade 3 cancers) and with lower screening sensitivity has implications for the organisation of screening programmes.
This low participation rate, as well as the StOEH screening rate, has implications for the generalizability of the results, as the sample was self-selective.
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