Sentence examples for screening for targeting from inspiring English sources

This allowed the dissection of the relative contribution of individual functional groups to the ligand-binding energy and assessment of the feasibility of fragment-based screening for targeting the VHL HIF-1α interface [ 145].

To screen for targeting at both alleles, a second PCR was performed with primers flanking the ZFN target site.

Amino acid sequences were screened for targeting peptides and associated cleavage sites using SignalP v3.0, ChloroP v1.1, TatP v1.0, and Wolf PSORT [ 67].

To screen for targeted and random integrations, Southern blot analysis was performed as previously described by Lofstrand Lab in Gaithersburg, Maryland.

The resulting G418-resistant clones were screened for targeted insertion by PCR and confirmed by Southern blotting.

We asked whether our new cell line model can be employed to screen for targeted drugs that can overcome resistance against masitinib in canine MC tumors.

Colonies surviving G418 (163 lg/mL active ingredient) and gancyclovir (2 lM) selection were screened for targeted recombination by Southern blot analysis.

In order to screen for targeted clones, primers were designed that produced an amplicon if the gene was not targeted and did not produce an amplicon if the gene was targeted.

A primer derived from the marker gene can be used with a primer derived from a sequence of the target locus which was not included in the knock-out construct to screen for targeted integration events.

To develop a more universal method to screen for targeted events, we optimized CRISPR/Cas9-mediated HDR using dsDNA donors that enable the incorporation of larger DNA sequences, including visible markers.

eSynth opens up a possibility to rapidly construct virtual screening libraries for targeted drug discovery.