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In principle, numerous ELISA plates for screening a range of cell lines with multiple supernatant samples can be processed simultaneously.
As a result of screening a range of marine organism extracts against L. amazonensis promastigotes, the promising natural product cristaxenicin A (36) was isolated (EC50 = 0.09 μM).
By screening a range of mammalian orphan receptors, Zhang et al. showed that obestatin appeared to be working via GPR39, a G protein-coupled receptor that is expressed in the stomach, in the intestines, and within the hypothalamus.
Therefore, we decided to optimize mono-culture models by systematically screening a range of 24-well tissue culture inserts from various providers (Corning®, Greiner Bio-one®, Millipore®, BD Falcon®, Nunc®, and Brand®) for each endothelial cell line, with the aim to increase TEER.
The Markov model constructed by McMahon et al. also compared four screening strategies in base-case, as well as four additional strategies in sensitivity analysis; these included standard screening, a range of different intensities of screening methods, as well as a no-screening option [28].
Specifically, our experiments have demonstrated the significant superiority of the best of the methods – referred to here as SUM-OKA -for screening a range of types of activity class when compared to a conventional screening system based on the Tanimoto coefficient.
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This study was designed to screen a range of ingredients and their activities on the gut microbiota.
In this study we screened a range of these ingredients in triplicate batch culture fermentations with known prebiotics as controls.
The third approach, used largely when the protein was very abundant, is to screen a range of proteases using crystallization, rather than gel electrophoresis, as the metric.
Using T-REX we have extensively screened a range of different physiological and pathological conditions.
This study shows the possibility of using MTS as a practical preclinical model to screen a range of PET tracers for breast cancer treatment monitoring.
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