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This chemical library was screened by using a combination of ligand guided and structure guided techniques.
All variables affecting the extraction process (sodium hydroxide concentration and volume, ramp and hold times, temperature and number of repeated extractions) have been screened by using a Plackett Burman design (PBD) as multivariate approach.
Variables affecting the extraction procedure were screened by using a 25−1 fractional factorial design and among them; sample amount, solvent volume, solvent ratio and extraction time were optimized by applying a rotatable central composite design (CCD).
In the present study, we investigated whether a CL binder was screened by using a CL-displaying BV.
Isolates were screened by using a GenoType kit (3) and multiplex PCR (4).
blaCTX-M genes were screened by using a multiplex PCR assay (30 ).
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Taspine was one of the active ingredients screened by using an endothelial cell membrane chromatography and showed inhibition against VEGFR-2.
In these studies, patients were screened by using an evaluation standard.
Samples were screened by using an MCPyV real-time PCR that was specific for the VP2/3 region.
Isolates from the 2006 and 2007 outbreaks were initially screened by using an 8-marker MLVA system (MLVA8) as described by Keim et al. (7 ).
More than 1,000 clinical isolates from 22 states were screened by using an itraconazole antifungal plate assay and the Etest to measure itraconazole MICs.
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