Exact(2)
In this screen, toxicity of each shRNA was assessed in two ways: (1) fold underrepresentation of the shRNA after infection with the shRNA-expressing lentivirus compared to its representation in the plasmid pool and (2) fold representation of the shRNA after infection and treatment with doxycycline compared to cells that were infected but did not receive doxycycline.
In vitro cytotoxicity results are used to screen toxicity and to estimate the IC50 of chemicals.
Similar(58)
This laboratory study screened toxicity of copper (Cu) stress in the fluvo-aquic system, investigated the ecological niche of ammonia-oxidizing archaea (AOA) and ammonia-oxidizing bacteria (AOB) communities and analyzed the response of AOA and AOB communities to Cu stress in the system.
Disclosed herein are organ chips that can be individually used or integrated together to form different microphysiological systems, e.g., for use in cell culturing, drug screening, toxicity assays, personalized therapeutic treatment, scaffolding in tissue repair and/or replacement, and/or pharmacokinetic or pharmacodynamics studies.
The present study was designed to seek a simple, effective, and oxidative stress-based biomarker system used for screening toxicity of nanomaterials.
Based on this screen, the toxicity of a number of tumor-suppressive miRNAs could be predicted solely on the basis of their 6mer seed sequences.
Electrostatic deposition of particles onto the surface of well-differentiated airway cells is a rapid and efficient means to screen for toxicity associated with exposure to fine and ultrafine particulate air pollution.
First, the NTP needs to modernize the mammalian assays used to screen for toxicity.
To screen cellular toxicity of the AMs, the alamarBlue assay was carried out according to manufacturer's protocol.
Furthermore, 7i, 7j, 7y and 7z were found to be non-toxic against mouse macrophage cell lines when screened for toxicity.
Clinical examination and routine screening bowel and bladder toxicity screen were undertaken and documented.
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