Sentence examples for screen promoter from inspiring English sources

Methylation-sensitive high-resolution melting was used to screen promoter methylation in a panel of 13 genes reported as methylated in breast cancer (RASSF1A, TWIST1, APC, WIF1, MGMT, MAL, CDH13, RARβ, BRCA1, CDH1, CDKN2A, TP73, and GSTP1) in 29 tumour pairs (16 ipsilateral and 13 contralateral).

The genomic approach used to screen promoters conferring high promoter-mediated noise in the sequenced S. cerevisiae strain EC1118 (Novo et al. 2009) was based on the method developed initially with Salmonella typhimurium (Freed et al. 2008).

Screening promoter methylation profiles in SGTs showed considerable heterogeneity.

Using high throughput sequencing analyses we screened promoter, coding regions and associated intronic splice junctions of the ST8SIA1 gene.

Based on these rationales, Ishiguro et al. [ 14] screened promoter and exonic regions of sigma receptor type 1 gene (SIGMAR1 or SR-BP1, OMIM No. *601978), and found two polymorphisms, G-241T/C-240T (rs1799729) and Gln2Pro (A61C, rs1800866).

Screening promoter methylation patterns in breast cancer patients could be an important step to develop treatment protocols that target the methylated gene and improve DFS in breast cancer patients.

Based on the assumption that heterogeneity of the cells may be driven by epigenetic changes, we screened promoter methylation of 96 candidate genes in parental breast cancer cells and putative breast CSC using Epitect Methyl qPCR Arrays (results are summarized in Figure  9).

New software includes a faster application-specific pattern-search, a new version (2.0) of the regular expression and Perl search as well as the possibility to load a fasta-format file with multiple sequences to screen for promoter patterns (including tardigrade-specific or general promoter motifs of interest).

In addition, we tested nine genes below the statistical threshold of the secondary screen using promoter fusions (Additional file 5).

To screen for promoter motifs, the sequences from -50 bp upstream to all identified TSS were analyzed using MEME[ 46].

In our study we elected to screen the promoter variant rs2069762, shown to influence IL-2 production up to 3-fold [ 35, 36] for a possible direct association.