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This graph more clearly depicts that the lowest scoring region corresponded to chromosome 4 of C. neoformans, where the MAT locus resides.
In this case, we found that m = k, defining exactly the same high scoring region likely to contain Cdk substrates, regardless of whether or not we choose to define the borderline region.
This is implemented by finding the highest scoring region within the alignment, and thus may omit divergent regions on the ends.
An interesting and high scoring region was also found in chromosome 12, where five individuals have a hetSH and three a homSH.
Thus, one cannot use the tail region of the Dpdf to assign the statistical significance for peptides, an Mpdf extrapolated from high but not very high scoring region is needed for this purpose.
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To transition from scoring markers to scoring regions, and for each region and in each sample, we calculated the weighted arithmetic mean for each Sk across the m markers in that region.
Average precision measures the performance of a system according to higher scoring regions overlapping with a TSS.
If such regions occur between highly scoring regions, an insertion or deletion call is made in the outlier region, depending on the relative size of the region on the query and reference maps.
If such a region occurs between highly scoring regions (p-value of 10e-6), an insertion or deletion call is made in the outlier region, depending on the relative size of the region on the query and reference maps.
This is typically repeated 10,000 times producing a null distribution of >108 scored regions.
Additionally, we scored regions in the L. (L).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com