We call these scoring functions Network RNAi Phenotype (NePhe) scoring functions, since we integrate both the network topology and RNAi screen data to derive the NePhe scores.
Polynomial scoring functions were built using as explanatory variables the energy terms present in the MolDock and PLANTS scoring functions.
Another focus is set on the implementation of scoring functions.
These four programs use various positioning algorithms and scoring functions.
To evaluate complexes against each other, scoring functions are required.
The problem stems from the additive nature of scoring functions.
In fact, scoring functions are usually implemented in docking programs.
Beside implemented scoring functions PScore, PMF04 and Drugscore, ParaDockS offers the possibility to derive and apply target specific scoring functions.
Linear scoring functions for these indicators were used to develop a soil quality index.
Statistical scoring functions derived from such subsets perform as well as scoring functions derived from the set of all pairwise interactions.
In general, three major classes of scoring functions can be distinguished: force-field based methods, knowledge-based potentials, and empirical scoring functions.
