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With a scoring cut-off of 25% to define low/high p27 values, low p27 (less than 25% of tumor cells positive) was an independent prognostic factor with a relative risk of 1.54 (P = 0.02) and this was durable over the extended median follow-up of 9 years (C Catzavelos and J Slingerland, manuscript in preparation).
Therefore, our risk score was superior to the PTS [ 23] and to the other score, which are modified PTS score cut offs [ 24- 26].
Q20 values were achieved by setting the sequence quality PHRED score cut-off value to 20.
The Mascot score cut-off value for a positive protein hit was set to 60.
The PHRED quality score cut-off value was set at 20 for the acquisition of Q20 values.
Others have proposed PSA and Gleason score cut-off points for selecting patients in whom the risk of nodal disease is low, obviating the need for PLND.
psRNATarget [ 47] was used, with a score cut off 4.0, UPE:50.9 to check previous predictions.
A score cut off value of 170 resulted in the grouping of 160 contigs into 55 super-contigs.
The items are summed on the basis of dichotomized scores (cut off: totally disagree and disagree = 0; other answers = 1).
We used six as a CORE index score cut off value, which means that all regions with score below six were excluded from the phylogenetic analysis.
The scoring cut-off point was determined using receiver operating characteristic (ROC) curve analysis.
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