Such multi-scale interpretation is enabled by the combination of individual peak ratio evaluation between equivalent nodes, topography partitioning, and cross-PTM score spanning the collective topography of (GCtimes GC) ROI.
The majority of ER+ (77%) and PgR+ (58%) specimens showed expression in greater than ⅓ of cells with a wide range of staining intensity; this resulted in a wide variation in the total Allred score spanning all categories from 2 to 8 (data not shown).
The 2 centimorgan (cM) region (97.11 cM 99.11 cM) with the highest LOD score spans 285.1 Kbp (from 15819851 16104972 on scaffold 10) and contains 24 candiate genes with putative function or known amino acid domains, of which PtARF1 is located at position 16037970.
Even if the maximumefficiency scores span up to several hundreds, the majority of users have anefficiency lower than 1, and most of them have values close to zero.
Many of the scores span extreme probability values above 0.5 (50,758) and below 0.5 (9084) as shown by the density and histograms seen in the figure.
The standard IUCN scoring we used spans 4 orders of magnitude, while Madagascar primate ED scores span <1, all primates <2, and all 4500 mammal species, ∼4 orders of magnitude.
The putative amphipathic helices with the highest scores span amino acids 22 41, 102 118, and 145 154.
RF case/control prediction probability scores span from 0 to 1, and for binary performance estimations we selected a case threshold of 0.45 or greater.
The scores span a continuum between a pure FCC arrangement (bottom right corner) and a pure HCP one (top left corner of the figure) and are widely distributed between the two extremes.
For these, the GO term path length varies between 2 and 15 with a mean around 6.4 [see Additional file 2: Figures S9 and S10] and the GO scores span the [0.5, 3.3] interval with the mean around 1.1 [see Additional file 2: Figures S11 and S12].
