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The tree with the lowest score (smallest number of changes) will be returned as the phylogeny, and internal gene orders with respect to the phylogeny can be treated as the estimated ancestral genomes.
The Longworth algorithm had the smallest difference between observed and predicted mean EQ-5D score, smallest MAE, and was the only algorithm to detect all 3 of the clinical difference.
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Final score: Small Fry 13-3.
Pharao is an open source software to align and score small molecules using pharmacophores.
Version 2.0 of CDK-Taverna provides two groups of workers that re-implement the work of Ertl et al to score small molecules for NP-likeness [14].
We considered only sRNA-target pairs with a score smaller or equal to 4. Three categories of cleavage profiles are defined by Addo-quaye et, al. [41].
A score smaller than 1 indicates 1/CR times greater variability between species.
We discarded all terms having a TF/IDF score smaller than 0.1.
Of 10,000 permutations, none showed a score smaller than the observed score (P < 10-4) (Additional file 10 Figure S7).
A 0.2 or higher score improvement was considered to be a large, clinically important improvement; other improvements were considered moderate (≥0.1 score), small (≥0.05 score), or very small (<0.05) [ 23, 28].
We identified all significant PSSM hits for the 111 TFs with a TFBS score smaller than the score/ P-value threshold.
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CEO of Professional Science Editing for Scientists @ prosciediting.com