The QTLs were deemed to exist only at positions where an LOD score exceeded the corresponding significant threshold.
When the NRS score exceeded 3/10, indicating the need for analgesic intervention, the Algoplus score was generally lower than the recommended trigger for analgesia (2/5).
The drug-target network (Additional file 2: Table S1) was constructed by linking the compound and target protein if the docking score exceeded the threshold values.
Note that data are shown only from those subjects whose vestibular-induced increase in motion-sickness score exceeded 3 after pretreatment with placebo.
We defined studies as high quality when the quality score exceeded eight (i.e., more than a half of total score), based on a definition from a previous systematic review [18].
Mechanical hyperalgesia (G2) was recorded, if gain of function (absolute or relative abnormality) was detected for mechanical pain threshold (MPT), mechanical pain sensitivity (MPS), pressure pain threshold (PPT) or if the dynamic mechanical allodynia (DMA) score exceeded 0 [19, 42, 43].
The correspondence ψ was calculated for each locus and a PWM motif match was called if this score exceeded 80% of the maximum score possible for a given PWM model (i.e., ψ/ψ max ≥ 0.80; R package: Biostrings, R function: matchPWM) [25,55,56].
Sub-analysis showed no significant difference in 28-day mortality in sepsis cases involving the lower-gastrointestinal tracts, but a trend for improvement in 28-day mortality was observed in sepsis cases where the infection focus could not be removed, such as pneumonia, and in severe sepsis cases whose APACHE II score exceeded 25.
Mechanical hyperalgesia (G2) was recorded if gain-of-function (absolute or relative abnormality) was detected for MPT, MPS, or PPT, or if the DMA score exceeded 0. Mixed gain (G3) was recorded in individuals with gain of both thermal and mechanical somatosensory function.
In 1993, Benet's average ACT score exceeded those of 195 public high schools in northern Illinois, second only to the Illinois Mathematics and Science Academy, a selective residential school for gifted students.
Subjects whose d' score exceeded ±2.0 (N = 4) were replaced.
