In addition, there are biases inherent to any such hospital-based study, especially given that in SSA there is major access and cost barriers to care, with a sizeable proportion of patients with neurodegenerative conditions who are never seen by health care providers thus limiting the scope of registries.
However in such cases, to permit causal inferences, a registry also would need to obtain samples from unaffected population controls, a task outside the scope of any registry.
This is outside the scope of a registry study but may be plausible in a smaller study.
The scope of this Registry is to identify, track, analyse, and store information on all cancer RCTs that have included PROs, and assess the quality of their PRO assessments.
The broad scope of this Registry is to identify, track, analyse, and store information on all cancer RCTs that have included PROs, and assess the quality of their PRO assessments.
Further analysis would require data that are beyond the current scope of cancer registries, such as participation rates in randomised clinical trials, where the more intensive experimental arm subsequently showed a survival benefit.
Analysis of such decision-making under time pressure involving medical perspectives (age, comorbidity) and patient's wishes and their quality of life equally is beyond the scope of an infarction registry, and we accept that there are good reasons for deciding on palliative treatment for some patients.
In this regard, part of the solution may be to optimize the scope and role of registries.
It broadened the scope of the sex-offender registry, mandating the full disclosure of a former offender's address, along with a photograph, and more; promulgated a form of indefinite detention, known as "civil commitment"; and, in a late addition to the bill, required that children as young as fourteen who had committed certain sex offenses be placed on the public registry.
Furthermore, attendant to the limited scope of the population-based registry, a bell-shaped distribution of the disease across the archipelago is assumed; but should cases cluster outside of the sampled areas, they may not be captured.
