Although it has been known for some time that the cationic complex [Cp*Ru(MeCN 3]PF6 (1; Cp*=pentamethylcyclopentadienyl) catalyzes the stereochemically uncommon trans-hydrosilylation of internal alkynes,[ 1– 3] it was recognized only recently that the scope of the underlying reactivity mode is actually much larger.
In this respect, the use of a small portion of an antigen, such as an epitope, instead of full-length proteins represents a potentially safer vaccine, since it limits the scope of potential cross-reactivity and concentrates the antibody response against the desired portion of an antigen.
However, this is solely based on structure (i.e. particle size, surface area, and percentage of vacancy sites) and does not encompass the full scope of factors contributing to Mn-oxide reactivity.
Encouraged by this observation, we undertook a study into the scope of the magnesium-catalyzed dehydrocoupling reactivity.
Having examined the general reactivity and scope of the developed sulfonamide synthesis, we next wanted to test the methodology by application to an array synthesis format.
The asymmetric inter- and intramolecular Heck and related reactions are also comprehensively reviewed, from their original development to recent advances in terms of substrate scope, reactivity, regio-, and enantioselectivity.
This unusual reactivity emphasizes the greater scope of mixed-metal chemistry as TMP self-deprotonation/metalation is unlikely to be reproduced (in a controlled manner) in a homometallic system.
Transmission of reactivity: indirect initiation, chain transfer.
In models with tertiles of reactivity, high SBP reactivity, compared with intermediate SBP reactivity, was associated with lower risk (hazard ratio [HR] =.498, 95% CI.335-.742, P =.001), whereas low SBP reactivity did not differ from intermediate reactivity.
Much suffering -- our own and other people's -- is borne of reactivity.
