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While they may not reflect the entire scope of output from the p53 regulatory network, our reporters are advantageous because they are validated functional sensors for p53 action in vivo.
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Part of the problem is the scope of his output.
Just as "Take Five" defined Brubeck and Desmond, it has been an ageless signature for Mr. Jamal — and maybe a bit of a burden, given the irreducible scope of his output since.
To determine the volume and scope of research output examining preparation of patients for people undergoing cancer-related surgical treatment, and the impact of pre-operative education on patient outcomes and health care utilisation.
I knew Lynch was an accomplished photographer and artist, but the sheer scope of his output in terms of quality and quantity is remarkable.
We further note that like all reporter systems, our p53 biosensors may not reflect the full scope of effector output regulated by this network, and activities visualized here could transmit only subsets of p53-mediated responses.
Chandler (1990) observed that enterprises across America, Britain and Germany had pursued scale and sometimes scope of multiple outputs to expand their business.
Advantages and challenges of the current methodologies are discussed, including the quality of input, validation, uncertainty, and scope of the outputs.
But if the full scope of Shostakovich's output has been left unexplored, at least the 15 symphonies have had their moment, by way of Valery Gergiev's cycle at Avery Fisher Hall.
It's a remarkable success story, but even more incredible is the artistic scope of Blum's output, which has somehow included a wealth-gap parable (The Purge), a Skype slasher (Unfriended), and a film that only the most battle-scarred of session musicians would even classify as horror (Whiplash).
Secondly, because the exact level and scope of input and output in healthcare services can never been determined with certainty, variation of service performance derived by these efficiency analyses may sometimes suffer because the resources consumed and outputs delivered were not fully captured.
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