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The mammalian brain is considered to be the most complex organ due to its cellular diversity, the variety and scope of its functions and its transcriptional regulation [92].
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Given the emerging importance of the UPS in neurons, a logical step towards better understanding the scope of its function in neurons and at synapses would involve an examination of the neuronal targets of the UPS.
While several studies have linked TRIM33 to transcriptional control, a genomewide assessment of TRIM33 occupancy has yet to be performed to define the scope of its regulatory function.
Analysis of an allelic series of point mutations in a gene, generated by N-ethyl N-nitrosourea (ENU) mutagenesis, is a valuable method for discovering the full scope of its biological function.
However, its relatively weak mechanical properties limit the scope of applicable functions.
Scope of expert functions implemented by a TP; 4.
This recursion is guided by the structure of a graph of translation tables that help compartmentalize the scope of various functions and identifier spaces, while relating these spaces for resource discovery, resolution, and routing.
Motivation for an organization to participate in a TP; Sources of funding attracted by the platforms; Scope of expert functions implemented by a TP; International activity; Criteria of effectiveness set by platform coordinators.
The introduction of digital relays has provided an unprecedented level of computational power in the substation and this has vastly increased the scope of the functions that can be delivered by any protection system.
Our results considerably increase the understanding and scope of energy functions derived from known biomolecular structures.
Both of these methods rely on GO annotation, which may limit the scope of gene/protein functions.
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CEO of Professional Science Editing for Scientists @ prosciediting.com