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The designs, scope of enrollment and study duration are too heterogeneous to permit head to head comparison with our study.
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In order to maximize the scope of our enrollment, an online recruitment method was proposed.
"We have always anticipated that the pace of enrollment will increase throughout the enrollment period".
Blood was drawn at day of enrollment.
Enrollment trajectories showed that the initial rate of accrual determined the subsequent rates of enrollment.
Date of enrollment of first patient: December 2011.
At Boston University and New York University, women make up 58% of enrollment.
The enrollment process had three steps: preliminary enrollment visit, daily questionnaire enrollment phase and confirmation of enrollment visit.
*Collected only in second year of enrollment.
Age 18-80 years on date of enrollment.
This is in part because most BioMarin studies did not collect molecular testing data as part of uniform enrollment criteria and also because the scope of this update is to report only on published Morquio A mutations.
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