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Accordingly, employing such chimeric immune receptors to redirect Tregs to sites of inflammation may be a useful therapeutic approach to alleviate a broad scope of diseases in which an uncontrolled inflammatory response plays a major role.
A unique biomedical delivery system (biolistics), for micro-sized powder formulation of drugs (typically protein- and/or DNA-based macromolecules) to be effectively and efficiently delivered into human skin or mucosal tissue for the treatment of a scope of diseases, has been proposed.
This fact may enable the broadening of the scope of diseases that a DMP addresses by making every disease equally financial attractive to care groups.
PRO concepts can also be generic (i.e., applicable in a broad scope of diseases or conditions as in the case of physical functioning), condition-specific (e.g., asthma-specific), or treatment-specific (e.g., measures of the toxicities of a class of drugs such as interferons or opioids).
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A careful assessment of all of these sources of variation should provide more confidence for molecular epidemiological applications including the detection and scope of disease outbreak clusters.
However, the ICD 9 coding system used in Canada does not capture the scope of disease or recognize the complexity of physician patient interactions.
3 In tobacco control research, such models have been used to understand the future scope of disease burden, 5 7 the potential effects of policies and regulations, 8 10 and the economic consequences of interventions.
As such, it is necessary to broaden detection to include other respiratory pathogens, to estimate the scope of disease burden and determine which respiratory pathogens are commonly identified in SARI patients.
Therefore, we examined non-influenza respiratory pathogens in children with severe acute respiratory illness (SARI) in Zambia, to estimate the scope of disease burden and determine commonly-identified respiratory pathogens.
Both neglected and under-reported, there is scant epidemiological data on leptospirosis therefore masking the true scope of disease prevalence and making reliable morbidity and mortality statistics difficult to ascertain [ 3].
There are three main limitations that reflect: 1) the relatively narrow scope of disease identified using hospitalized AMI; 2) changes to AMI diagnosis and classification; and, 3) reliance on extrapolating unobserved events.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com