Only model knowledge gaps [ 8] were targeted, not scope gaps.
The gaps in a metabolic network can also be classified as either scope gaps or knowledge gaps.
Since the iJO1366 tRNA charging reactions are blocked by scope gaps, these important reactions cannot be used in the model.
Many of these are scope gaps, caused by the limited scope of the metabolic network, and these have previously been identified [ 8, 10].
Potential surveillance scope gaps: These gaps occur where a surveillance system is established, but its type, range of events covered, and scope of information it is designed to collect does not meet its purpose.
Scope gaps are those that exist because the scope of most metabolic network models does not include features like macromolecular degradation or the use of charged tRNAs in protein synthesis.
I am most interested, in other words, with the shape and scope and gaps of my childhood collection, and with my childhood, and with the way that childhood has filtered through and shaped all stages of my life to the present.
For the scope of this gap analysis, the timeframe allocated to searching for datasets had not yet reached this point of diminishing returns.
Nanostructures of narrow band-gap semiconductiors such as PbS provide a large scope for band-gap engineering as strong quantum confinement effects can alter the bulk band-gap value all the way from 0.41 to 2.3 eV, rendering the material transparent in most of the visible range of the electromagnetic spectrum.
At the same time, the relatively small size of the BAC clones also is a shortcoming of maps created from this panel: the short span of each member within the pool limits its scope to traverse gaps (>100 Kbp) caused by incomplete marker coverage, by marker clustering, or through the presence of large repetitive regions of DNA (Figure 1d, e).
