Your English writing platform
Discover LudwigSuggestions(1)
Exact(6)
The Scope algorithm iteratively updates a set A of metabolites that a reaction system can synthesize.
The notion of downstream can be made quantitative through the Scope algorithm [ 60, 61].
We have used the Scope algorithm to define a distance of a reaction in the global reaction set from nutrient metabolites.
A limitation of the Scope algorithm in comparison to constraint-based frameworks like FBA is its inability to deal properly with the self-generating (autocatalytic) nature of certain cofactor metabolites (e.g., ATP, NADH) in the network [ 70, 71].
Specifically, the distance of a reaction from the nutrient metabolites in the seed set is defined as the iteration number i of the Scope algorithm when that particular reaction contributes its products to A(i+1).
Following Kun et al [ 71], we included in the seed set the autocatalytic metabolites listed in Additional File 2 Table S2 (in addition to the nutrient metabolites in our minimal environment) when computing the distance of reactions with the Scope algorithm.
Similar(54)
Several considerations were taken into account in the design of search strategies with regard to datasets, search scope, and algorithms.
In our experiments, the manual segmentations were employed, as the scope of our algorithm is to detect junctions, crossovers, and end-points.
The scope of an algorithm may be expanded to capture a system at an arbitrary level of detail, but by then, what are the advantages of using the term algorithm?
We now expand the scope of this algorithm and present the software, Saguaro.
Finding them has been beyond the scope of computer algorithms.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com