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The phrase "scientific issue" is correct and usable in written English.
You can use it when discussing a problem or topic that pertains to scientific inquiry or research.
Example: "The scientific issue at hand requires thorough investigation and analysis to reach a conclusion."
Alternatives: "scientific problem" or "scientific matter".
Exact(58)
It looks like a scientific issue, but it isn't.
And waste disposal is primarily a political, not a scientific, issue.
"One is in many ways a political issue, but the other is a scientific issue.
The EC is trying to make a delay look like a scientific issue".
This is a complex scientific issue suddenly confronting people, and it's frightening.
It's a disingenuous attempt to score points on a highly polarized scientific issue.
Experts say the scientific issue it raises is an important one.
In 1791, however, a completely new scientific issue began to obsess him: the theory of colour.
"The ultimate control of cancer is as much a public policy issue as it is a medical and scientific issue".
"If you are influencing the public about a scientific issue, there has to be some responsibility taken by the artist".
Fixing the monopolies of global capitalism is not a scientific issue, nor will growing GMO usage make matters worse.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com