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Changes associated to stage transition (1 to 2, 2 to 3, 3 to 4) could be found, but were difficult to relate to a coherent scheme of progression.
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The schematic progression in time of myelogenous leukemia is shown in Figure 1. Figure 1 A scheme of myelogenous leukemia progression in time.
The apparently greater benefit of the higher doses of CC-930 may have reflected an imbalance in risk of progression despite the randomization scheme.
No impact of chemotherapy scheme modifications on progression free survival was found in the aforementioned study by R. K. Hanna et al. [ 18], and our study demonstrates the same result.
That aggregate alpha-synuclein and tau pathologies may be seeded and transmissible throughout the cerebrum presents an attractive means to explore Braak staging (a regional and temporal scheme for the progression of these inclusion body pathologies) and vulnerable cell populations in specific genetic backgrounds.
"Teachers can't rely on progression based on experience and so rates of progression are falling".
There is also a sense of progression for each warrior.
The rogue spirit of progression can also be infectious.
Still, one doesn't exactly get a sense of progression.
What type of progression might we see?
We were interested in determining the existence of a progression scheme between superficial carcinomas (stage 1), invasive carcinomas (stage 2 and 3) and metastatic carcinomas (stage 4) based on a gradual accumulation of genomic alterations, with alterations occurring specifically at each step of progression.
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