Exact(3)
The influences of treatment schedule, single dose per cycle, and infusion time were not analyzed as this safety analysis was focused on FOLFOX4 regimen in the six studies.
Various risk factors have been reported concerning oxaliplatin-induced neurotoxicity, including treatment schedule, single dose per cycle, cumulative dose, infusion time, pre-existing peripheral neuropathy, and surgery [ 18].
Also we stratified by PQ dose category: low (< 0.4 mg/kg) medium (≥ 0.4 to < 0.6 mg/kg); and high (≥ 0.6 mg/kg dose); by schedule (single dose day 1 or 2, single dose day 3 or 4, and multiple dose days 1 to 7) and grouped the 8AQ drugs as PQ and other.
Similar(57)
In order to enhance vaccine efficacy and induce long-term, protective immunity, the choice of route (intramuscular [3], [4], subcutaneous [5], [6] or intranasal [4], [7]), adjuvant (Alhydrogel [5], [6], viral vectors [3], polyester microparticles [4], or lipid A mimetics [7]), and vaccination schedule (single-dose [4], [5], [7] or multiple-doses [3], [6]) must all be considered.
Three treatment protocols were used: early schedule, late schedule and single dose.
Unfortunately due to the difference in treatment schedule (bendamustine, single dose; SAHA, daily dose) and toxicity issues, we could not establish an effective treatment schedule that involves both bendamustine and SAHA.
In additional notes on Pandemrix the Committee said: "The vaccine should preferably be used as a two-dose schedule, but a single dose may be sufficient in adults aged 18 to 60 years.
The immunization schedule is a single dose given as soon as possible after 14 weeks of age.
Infants allocated the combination schedule received a single dose of PHiD-CV10 at the time of randomisation (table 1).
Similarly to what was observed with LMeC, the three-week dose schedule produced a better anti-tumour effect than the single dose schedule (p < 0.05).
The decision for a single dose schedule at 14 months of age was based on epidemiological, programmatical and economical reasons [2].
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