Sentence examples for schedule of dosing from inspiring English sources

The aim is to study the effectiveness of dexamethasone to prevent the occurrence of a pain flare after radiotherapy for painful bone metastases and to define the optimal schedule of dosing.

In the present study we examined neurobehavioral effects of TCVs using both an accelerated vaccine primate schedule and the recommended pediatric schedule, neither of which appeared to affect neurobehavioral outcomes, thus suggesting that the toxicokinetics of EtHg in infant primates is not a limiting factor when using an accelerated schedule of dosing.

Although oral etoposide potentially offers a superior schedule of dosing (Slevin et al, 1989), this has been questioned (Girling, 1996).

PCV7 was licensed on the basis of a randomized controlled trial in The Northern California Kaiser Permanente health care system, which demonstrated 97% efficacy against PCV7-serotype IPD when administered on a schedule of dosing at 2, 4, 6, and 12 15 months of age (9 ).

The 60-patient two-month clinical trial of the medication, lercanidipine, was conducted in response to a 2002 Food and Drug Administration request for more data on the effectiveness of a proposed schedule of doses, Forest said.

Although the biweekly dosing schedule used in this study demonstrated apparent activity, the serum levels of antibody measured here appear to be less than those in studies of NHL, where a weekly schedule of dose administrations has shown antitumor activity [ 42- 44].

The adolescent phase IIb/III study (V72P10; NCT00661713) enrolled 1,631 subjects in Chile from June 2008 to determine the number and schedule of doses necessary to establish immunogenicity, and the tolerability of those doses, as described by Santolaya et al. [ 29].

Thus, the effects may be context-dependent or require a more rigorous analysis of dosing schedule or pharmacokinetics.

It is important to note that the form of the additivity model does not include information about scheduling of dosing, because single-chemical data were available only with the SLT protocol.

Nevertheless, further studies addressing the optimization of dosing schedules, pharmaceutical drug formulations, and patient selection are needed.

The potential benefits of amifostine may have been obscured by inability to provide full amifostine doses due to toxicity associated with infusion, scheduling of doses, and inadequate follow-up to monitor severity of esophagitis over time.