This paper describes a systematic review of the literature in which an attempt has been made to determine which schedule of administration is superior.
Ongoing clinical trials will help clarify the settings in which these agents are of greatest therapeutic value, the optimal schedule of administration, toxicities associated with chronic administration, and hopefully, provide additional insight into the biology of lung cancer.
Timing, dose and schedule of administration of steroid therapy and other eventual immunosuppressive treatments were recorded.
These data indicate that further clinical trials in colorectal carcinoma with this agent and schedule of administration are not warranted.
These possible benefits and the high rate of severe toxicity define a very narrow therapeutic index for concurrent gemcitabine-based chemoradiation given by this schedule of administration.
The optimum schedule of administration of conjugate vaccines is not yet well defined.
Of interest is the fact that the effects of lithium, which has a powerful immunological action [27], were independent on the schedule of administration.
Secondary comparisons found differences in efficacy possibly related to schedule of administration of chemotherapy.
The efficacy of a treatment is strongly dependent on its dosage and schedule of administration.
However no clear data are available on the optimal schedule of administration of this drug.
Using this schedule of administration, fosquidone has no significant antitumour activity in this group of tumours.
