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Additionally, there was dependence on post-treatment time to observe optimal biomarker changes but these responses were less dependent on the schedule of addition of DNA damaging agent and V158411.
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The evaluation and scheduling of additions to lines (i.e., links and stations) are performed jointly by this model.
A full schedule of the additions is listed on the festival's Web site, www.fringenyc.org.
In this trial, patients with metastatic melanoma were randomized to either ipilumumab alone at a dose of 10 mg/kg every 3 weeks for 4 cycles followed by maintenance of ipilimumab every 12 weeks or to the same dose and schedule of ipilumumab in addition to GM-CSF at 250 µg subcutaneously on days 1-14 of 21-day cycles for 4 cycles.
Given the large number of vaccinations already included in the routine childhood immunization schedule, the addition of another "shot" may not sound attractive to parents and certainly not to their children.
With this schedule, the addition of decitabine appears to reduce rather than increase the efficacy of carboplatin in partially platinum-sensitive ovarian cancer and is difficult to deliver.
Moisture transfer occurred between consecutive layers of compacted wastes and a moisture addition schedule of 2 days of as-received conditions and 1 day of moisture addition was recommended.
Furthermore, there is evidence for anti-angiogenic effects of this schedule in addition to the anti-microtubule properties [ 57].
Although early clinical data from phase I and phase II dose-dense paclitaxel trials in advanced ovarian cancer were promising, the results from phase III studies in have been inconsistent as a result of differences in paclitaxel dose, carboplatin AUC and schedule, addition of bevacizumab as well as different ethnic populations.
In addition, a schedule of task execution can be represented graphically in what is called a Gantt chart.
Therefore, a second generation of trials was planned to define further the best taxane, the optimal schedule of administration, and whether the addition of further agents might be of some benefit.
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