Herd immunity was also observed for every vaccine scenario, since prevalence declined in age groups not targeted by the vaccine.
In the base-case scenario, chlamydia prevalence in the strategy A scenario (no screening, no vaccination) was 3.73% in women and 2.90% in men.
Our model showed that in a no-vaccination scenario, HPV16 prevalence increases from 3%to8%8% with transition to gender-similar sexual behavior.
The survey collected data on local capabilities (including typical management of three clinical scenarios) and prevalence of a coordinator for pediatric emergency care.
With targeted optimistic and realistic scenarios, the prevalence of resistance was modestly reduced with considerable erosion (up to 70%) of infections prevented.
The models also enabled us to evaluate the effect of various vaccination scenarios on prevalence and infection rates.
Using sensitivity analysis (Schlesselman, 1978) we developed realistic scenarios of prevalence and strength of these risk factors on screened and not screened groups, and explored the impact of residual confounding bias.
Serious classification errors occurred more often under the scenario where prevalences were clustered around 0.05 (triangular distribution) than under the uniform scenario because a higher proportion of data sets had HPV positivity between 0 - 20% because of the peaked nature of the sampling distribution (35%vs.18%%).
Situations like this may account for the observed improvement in confounding control in the ATC level 4 aggregation (e.g., RR of 0.83 in 20% exposure prevalence scenario) compared with scenarios that used ATC level 5 (e.g., RR of 0.88).
The performance characteristics of the algorithm were excellent, with a sensitivity of over 90% for automatic codes, either in the 5% prevalence scenario or in the 50% prevalence scenario, which was minimally affected when mother's name was not available.
