These children were retained in the analysis of scar reaction since we considered it unlikely that current chloroquine treatment would have affected the scar formation.
However, at the occasion of revision operations it becomes apparent that the textile gets integrated into a tissue with more or less scar reaction.
Scarring, allergic reactions, leaking of breast implants and infection are all potential risks.
Though some studies have documented that PPD (tuberculin purified protein derivative or Mantoux test) and scar reactions get larger with revaccination, 23 24 others have found no effect of revaccination on protection against pulmonary tuberculosis but found that it might improve protection against leprosy.
2 As with other types of tattoos, a variety of adverse effects have been observed with permanent makeup, such as fanning, fading, and scarring; 3 granulomatous inflammatory reactions; 4 allergic contact dermatitis; 5 phototoxicity; 6 hypomelanosis; 7 and infections.
Additionally, although we have focused on axonal and circuit repair, our disease model can be easily adapted to visualize and probe other injury responses, such as inflammation, infection, immune reactions and scarring.
Apart from the three monthly routine surveillance visits to all children in the study area, all children enrolled in the trial were visited two and six months after inclusion to assess tuberculin reaction and BCG scarring.
Overall, the most common issues are: infection, allergic reactions, swelling, bleeding, scarring, pain and slow healing time.
Scarring can also be caused by inflammation in reaction to allergens or deep cuts and injuries.
