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Cost of the light source and scarce knowledge of the benefits of PDT by physicians limit the spread of the treatment throughout the country.
Despite this situation and despite the broad variety of existing integrated approaches, there is scarce knowledge of the extent to which such technologies are being assessed in integrated ways.
Using this method, we show that with a scarce knowledge of the node affiliations, multiresolution methods can be adjusted to retrieve the Autonomous Systems, significantly improving the results of classical single-resolution methods.
However, prognostic stratification and treatment decision for the intermediate risk category, that mostly comprises AML patients with normal cytogenetics (CN-AML), has been difficult due to the clinical heterogeneity and scarce knowledge of the molecular alterations underlying this large AML subgroup.
Aim of this paper is an overview on researches developed in this field to compare general approaches and measurements protocols: the scarce knowledge of the physiological mechanisms, as well as the lack of shared methods, techniques, tools and procedures represent the weak point of this research.
Taking into account the scarce knowledge of the characteristics of CIH at the molecular level, the high proportion of solo-LTRs is difficult to interpret.
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Governments have a legitimate concern for the well-being of citizens and national security, but divergence on how these concerns are defined and scarce knowledge of how the Internet actually works can result in ill-conceived proposals.
Studies involving the natural hosts of BTV are limited by the complexity of the system, the scarce knowledge of their immune system, and the need to have an animal facility with biosafety level 3. To circumvent some of these problems, an adequate system would be the use of adult mice because of the knowledge of its genetics and its manageability.
According to a systematic review, the current low coverage of HPV immunisation by active offer is due to: scarce knowledge of HPV and the HPV vaccines; high costs in countries where these costs are incurred by the recipient or his/her parents; perceived low efficacy of the vaccine; and alleged and real adverse events to HPV vaccines [ 37].
Rational tools developed to increase the yet scarce knowledge on the purification processes of complex biologicals are discussed as alternative to empirical, "black-boxed" based strategies classically used for process development.
Most importantly, the ISH analysis enhances the current scarce knowledge on the cellular distribution of these miRNAs within the cornea.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com