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CTLA-4 blockade might not benefit patients in Groups 1 and 3 (those with CTLA-4low tumor cells) because of the scant levels of soluble CTLA-4 to neutralize.
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Crucially, we found that hLE morphology and p63α expression was similar on RAFT TEs and HAM: hLE on both were tightly packed and displayed a cobblestone morphology, with scant cytoplasm and high levels of putative stem cell marker p63α.
However, information is scant regarding whether the adverse levels of glucose homeostasis variables (glucose, insulin, and insulin resistance index) in childhood persist over time and predict pre-diabetes and type 2 diabetes and other cardiometabolic risk factors in apparently healthy young adults.
There's even scant evidence to suggest that the levels of sulfites, a preservative in wines, has any impact on a wine drinker's health.
In a shrinking economy, a country's debt-to-GDP ratio rises rather than falls, and Europe's recession-ridden crisis countries have now saved themselves into a depression, resulting in mass unemployment, alarming levels of poverty and scant hope.
Research examining the effects of extreme cold on the skin in individuals of different levels of fatness is scant, as researchers have mainly focused on core temperature and tolerance to cold environments.
The site's frustration with Chicago underscores how scant our access is to public records at most levels of government.
However, only scant information exists on the effect of Candida colonization on serum levels of diagnostic biomarkers.
Consistent with this possibility, in DLB cases Cathepsin D-immunoreactive lysosomes of normal size were scant, and pyramidal cells contained enlarged lysosomes (Figure 2H J, N) and increased levels of LC3 immunoreactivity (Figure 2K M, O) compared to control cases.
However, only scant information is available on the effect of Candida colonization on the serum levels of BDG, Candida mannan or Candida DNA [ 12- 14].
In the United States, studies comparing states like Virginia with scant regulation against those like Wisconsin with strict rules have not found much difference in levels of corruption or public trust, several scholars said.
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