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"There is lots of evidence that points to the pathway being involved, but we need to do special scanning to show that what's happening to the mice is happening to humans," said Mallucci.
In another seminal paper, published in the journal Nature Medicine in 1995, researchers in London used P.E.T. brain scanning to show that during and after a migraine attack, blood flow increases to parts of the brain stem.
Dean Mobbs, of the University of Cambridge, UK, and colleagues, for example, have used brain scanning to show how choking is manifested in the brain.
In a recent study with the femoral neck ligation ligamentum teres sectioning model, we applied three dimensional CT scanning to show the close coupling of acetabular deformation to femoral head deformation.
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The last one was: "I need a scan to show which natural therapy will best penetrate the tumour".
Among those who have provided further evidence are researchers at the Helsinki University of Technology, who used MEG scans to show mirror-neuron deficits in autistic teen-agers and adults.
In a previous study, Maguire used brain scans to show that a brain region at the rear of the hippocampus known to be involved in learning directions and locations is enlarged in London taxi drivers.
Neuroscientists exploring the machinery of language now regularly use "Jabberwocky sentences" during brain scans, to show that meaning and grammar are processed quite separately in the brain.
Previous studies have used functional magnetic resonance imaging (fMRI) scans to show that similar areas of the brain are activated when someone is in pain and when they see another person in pain.
I find myself more concerned with aspects such as checking that the same symbols are used consistently throughout the text, or putting arrows on photos of clinical scans to show the nonspecialist which white blob is actually the tumour.
A 2012 study led by David Nutt, the Edmond J. Safra Professor of Neuropsychopharmacology at Imperial College of London, used a brain scan to show how ecstasy consumption affects emotions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com